This HLA table is to be used for HLA typing and unacceptable antigen listing in Eurotransplant for HLA-DRB3/4/5.
The alleles with XX in the antigen list are only to be used for patient HLA typing registration.
Assays used or typing donors and/or recipients in Eurotransplant affiliated laboratories must be capable of determining the presence (with or without ambiguities) of the alleles listed in red.
| Allele | ET Match Determinant Broad |
|---|---|
| DRB3*01:01 | DR52 |
| DRB3*01:02 | DR52 |
| DRB3*01:16 | DR52 |
| DRB3*01:XX | DR52 |
| DRB3*02:01 | DR52 |
| DRB3*02:02 | DR52 |
| DRB3*02:03 | DR52 |
| DRB3*02:04 | DR52 |
| DRB3*02:05 | DR52 |
| DRB3*02:06 | DR52 |
| DRB3*02:09 | DR52 |
| DRB3*02:10 | DR52 |
| DRB3*02:11 | DR52 |
| DRB3*02:12 | DR52 |
| DRB3*02:13 | DR52 |
| DRB3*02:16 | DR52 |
| DRB3*02:17 | DR52 |
| DRB3*02:19 | DR52 |
| DRB3*02:21 | DR52 |
| DRB3*02:22 | DR52 |
| DRB3*02:23 | DR52 |
| DRB3*02:24 | DR52 |
| DRB3*02:25 | DR52 |
| DRB3*02:32 | DR52 |
| DRB3*02:XX | DR52 |
| DRB3*03:01 | DR52 |
| DRB3*03:02 | DR52 |
| DRB3*03:XX | DR52 |
| DRB4*01:01 | DR53 |
| DRB4*01:02 | DR53 |
| DRB4*01:03 | DR53 |
| DRB4*01:03N | |
| DRB4*01:05 | DR53 |
| DRB4*01:07 | DR53 |
| DRB4*01:15 | DR53 |
| DRB4*01:17 | DR53 |
| DRB4*01:20 | DR53 |
| DRB4*01:XX | DR53 |
| DRB4*02:01N | |
| DRB4*03:01N | |
| DRB5*01:01 | DR51 |
| DRB5*01:02 | DR51 |
| DRB5*01:05 | DR51 |
| DRB5*01:08N | |
| DRB5*01:10N | |
| DRB5*01:XX | DR51 |
| DRB5*02:02 | DR51 |
| DRB5*02:03 | DR51 |
| DRB5*02:04 | DR51 |
| DRB5*02:06 | DR51 |
| DRB5*02:XX | DR51 |
Based on Well-documented CIWD 3.0.0 EURO population. Common, intermediate and well-documented HLA alleles in world populations: CIWD version 3.0.0, Hurley et al., HLA, 2020;95(6):516–531.
ET Match Determinants based on 2008 HLA dictionary, Holdsworth et al., Tissue Antigens 2009